4rma: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==Crystal structure of the FERM domain of human ezrin==

~~The entry~~ 4rma is ~~ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4rma]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RMA OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RMA FirstGlance].

~~Authors~~: ~~Phang~~, J.M.~~, Harrop, S~~.J., ~~Duff, A~~.P., ~~Wilk~~, K.E., ~~Curmi, P~~.M.G.

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[4rm8|4rm8]], [[4rm9|4rm9]]</td></tr>

~~Description~~: ~~Crystal structure~~ of the ~~FERM domain~~ of ~~human ezrin~~

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rma FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rma OCA], [http://pdbe.org/4rma PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rma RCSB], [http://www.ebi.ac.uk/pdbsum/4rma PDBsum]</td></tr>

[[Category: ~~Unreleased Structures~~]]

</table>

[[Category: ~~Phang~~, ~~J.M~~]]

== Function ==

[[Category: ~~Duff~~, ~~A.P~~]]

[[http://www.uniprot.org/uniprot/EZRI_HUMAN EZRI_HUMAN]] Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.<ref>PMID:17881735</ref> <ref>PMID:18270268</ref> <ref>PMID:19111582</ref>

[[Category: ~~Curmi~~, P.M.G]]

== References ==

[[Category: Wilk, K.E]]

[[Category: ~~Harrop, S.J~~]]

__TOC__

</StructureSection>

[[Category: Curmi, P M.G]]

[[Category: Duff, A P]]

[[Category: Harrop, S J]]

[[Category: Phang, J M]]

[[Category: Wilk, K E]]

[[Category: Erm]]

[[Category: Ezrin]]

[[Category: Ferm domain]]

[[Category: Membrane cytoskeleton linker]]

[[Category: Peptide binding protein]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Crystal structure of the FERM domain of human ezrin==
+<StructureSection load='4rma' size='340' side='right' caption='[[4rma]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
-The entry 4rma is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4rma]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RMA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RMA FirstGlance]. <br>
-Authors: Phang, J.M., Harrop, S.J., Duff, A.P., Wilk, K.E., Curmi, P.M.G.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4rm8|4rm8]], [[4rm9|4rm9]]</td></tr>
-Description: Crystal structure of the FERM domain of human ezrin
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rma FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rma OCA], [http://pdbe.org/4rma PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rma RCSB], [http://www.ebi.ac.uk/pdbsum/4rma PDBsum]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
-[[Category: Phang, J.M]]
+== Function ==
-[[Category: Duff, A.P]]
+[[http://www.uniprot.org/uniprot/EZRI_HUMAN EZRI_HUMAN]] Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.<ref>PMID:17881735</ref> <ref>PMID:18270268</ref> <ref>PMID:19111582</ref>
-[[Category: Curmi, P.M.G]]
+== References ==
-[[Category: Wilk, K.E]]
+<references/>
-[[Category: Harrop, S.J]]
+__TOC__
+</StructureSection>
+[[Category: Curmi, P M.G]]
+[[Category: Duff, A P]]
+[[Category: Harrop, S J]]
+[[Category: Phang, J M]]
+[[Category: Wilk, K E]]
+[[Category: Erm]]
+[[Category: Ezrin]]
+[[Category: Ferm domain]]
+[[Category: Membrane cytoskeleton linker]]
+[[Category: Peptide binding protein]]