5elh: Difference between revisions
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''' | ==Crystal structure of mouse Unkempt zinc fingers 1-3 (ZnF1-3), bound to RNA== | ||
<StructureSection load='5elh' size='340' side='right' caption='[[5elh]], [[Resolution|resolution]] 1.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5elh]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ELH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ELH FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5elk|5elk]]</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5elh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5elh OCA], [http://pdbe.org/5elh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5elh RCSB], [http://www.ebi.ac.uk/pdbsum/5elh PDBsum]</span></td></tr> | |||
[[Category: | </table> | ||
[[Category: Patel, D | == Function == | ||
[[http://www.uniprot.org/uniprot/UNK_MOUSE UNK_MOUSE]] Sequence-specific RNA-binding protein which plays an important role in the establishment and maintenance of the early morphology of cortical neurons during embryonic development. Acts as a translation repressor and controls a translationally regulated cell morphology program to ensure proper structuring of the nervous system. Translational control depends on recognition of its binding element within target mRNAs which consists of a mandatory UAG trimer upstream of a U/A-rich motif. Associated with polysomes (PubMed:25737280).<ref>PMID:25737280</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Murn, J]] | |||
[[Category: Patel, D J]] | |||
[[Category: Shi, Y]] | |||
[[Category: Teplova, M]] | [[Category: Teplova, M]] | ||
[[Category: Zarnack, K]] | [[Category: Zarnack, K]] | ||
[[Category: | [[Category: Ccch zinc finger]] | ||
[[Category: Rna binding protein-rna complex]] | |||
[[Category: Rna-binding protein]] | |||
[[Category: Unkempt]] | |||
Revision as of 13:50, 9 December 2015
Crystal structure of mouse Unkempt zinc fingers 1-3 (ZnF1-3), bound to RNA
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