Complexin: Difference between revisions

From Proteopedia
Jump to navigationJump to search
Michal Harel (talk | contribs)
No edit summary
Michal Harel (talk | contribs)
No edit summary
Line 4: Line 4:




'''Complexin''' (CPLX) is the protein which binds the SNARE protein complex with high affinity.  CPLX acts as both inhibitor and facilitator of vescicle fusion and neurotransmitter release at the synapse.  CPLX clamps SNARE complexes to prevent vescicle fusion while in another conformation it releases the SNARE complex allowing fusion.<ref>PMID:11742345</ref>
'''Complexin''' (CPLX) is the protein which binds the SNARE protein complex with high affinity.  CPLX acts as both inhibitor and facilitator of vescicle fusion and neurotransmitter release at the synapse.  CPLX clamps SNARE complexes to prevent vescicle fusion while in another conformation it releases the SNARE complex allowing fusion.<ref>PMID:12200427</ref>
</StructureSection>
</StructureSection>
==3D structures of complexin==
==3D structures of complexin==

Revision as of 09:38, 14 December 2015


Human complexin (magenta) as part of the SNARE complex (VAMP2 - grey; syntaxin - green; SNAP25 (pink and yellow) (PDB entry 3rk3)

Drag the structure with the mouse to rotate

3D structures of complexin

Updated on 14-December-2015

1kil – CPLX + SNARE – rat

3rk3, 3rl0 - CPLX + SNARE – human

References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky