Cruzain: Difference between revisions
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<StructureSection load='1me3' size='350' side='right' caption='Structure of cruzain complex with methylketone inhibitor (PDB entry [[1me3]])' scene=''> | <StructureSection load='1me3' size='350' side='right' caption='Structure of cruzain complex with methylketone inhibitor (PDB entry [[1me3]])' scene=''> | ||
'''Cruzain''' (Cru) is the major cysteine protease present in ''Trypanosoma cruzi'' which is the parasite causing Chagas disease. <ref>PMID: | '''Cruzain''' (Cru) is the major cysteine protease present in ''Trypanosoma cruzi'' which is the parasite causing Chagas disease. <ref>PMID:7707373</ref> | ||
</StructureSection> | </StructureSection> | ||
==3D structures of cruzain== | ==3D structures of cruzain== | ||
Revision as of 11:05, 15 December 2015
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3D structures of cruzain
Updated on 15-December-2015
1aim, 2aim, 1me3, 1me4 – Cru catalytic domain + methylketone inhibitor – Trypanosoma cruzi
1f29, 1f2a, 1f2b, 1f2c, 1ewo, 3lxs - Cru catalytic domain + vinyl sulfone derived inhibitor
1ewl, 1ewm – Cru catalytic domain + methylbutane inhibitor
1ewp - Cru catalytic domain + MOR-Leu-HPQ
