4xjv: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==Crystal structure of human thioesterase 2==

~~The entry~~ 4xjv is ~~ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4xjv]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XJV OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XJV FirstGlance].

~~Authors~~: ~~Ritchie~~, M.K., ~~Kridel~~, S.J., ~~Lowther, W~~.T.

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Oleoyl-[acyl-carrier-protein]_hydrolase Oleoyl-[acyl-carrier-protein] hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.2.14 3.1.2.14] </td></tr>

~~Description~~: ~~Crystal structure~~ of ~~human~~ thioesterase 2

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xjv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xjv OCA], [http://pdbe.org/4xjv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xjv RCSB], [http://www.ebi.ac.uk/pdbsum/4xjv PDBsum]</td></tr>

[[Category: ~~Unreleased Structures~~]]

</table>

[[Category: Lowther, W.T]]

== Function ==

[[Category: Ritchie, M.K]]

[[http://www.uniprot.org/uniprot/SAST_HUMAN SAST_HUMAN]] In fatty acid biosynthesis chain termination and release of the free fatty acid product is achieved by hydrolysis of the thio ester by a thioesterase I, a component of the fatty acid synthetase complex. The chain length of the released fatty acid is usually C16. However, in the mammary glands of non-ruminant mammals, and in the uropygial gland of certain waterfowl there exists a second thioesterase which releases medium-chain length fatty acids (C8 to C2) (By similarity).

[[Category: ~~Kridel, S.J~~]]

__TOC__

</StructureSection>

[[Category: Kridel, S J]]

[[Category: Lowther, W T]]

[[Category: Ritchie, M K]]

[[Category: Closed conformation]]

[[Category: Fatty acid synthase]]

[[Category: Hydrolase]]

[[Category: Lipid metabolism]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Crystal structure of human thioesterase 2==
+<StructureSection load='4xjv' size='340' side='right' caption='[[4xjv]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
-The entry 4xjv is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4xjv]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XJV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XJV FirstGlance]. <br>
-Authors: Ritchie, M.K., Kridel, S.J., Lowther, W.T.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Oleoyl-[acyl-carrier-protein]_hydrolase Oleoyl-[acyl-carrier-protein] hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.2.14 3.1.2.14] </span></td></tr>
-Description: Crystal structure of human thioesterase 2
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xjv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xjv OCA], [http://pdbe.org/4xjv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xjv RCSB], [http://www.ebi.ac.uk/pdbsum/4xjv PDBsum]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
-[[Category: Lowther, W.T]]
+== Function ==
-[[Category: Ritchie, M.K]]
+[[http://www.uniprot.org/uniprot/SAST_HUMAN SAST_HUMAN]] In fatty acid biosynthesis chain termination and release of the free fatty acid product is achieved by hydrolysis of the thio ester by a thioesterase I, a component of the fatty acid synthetase complex. The chain length of the released fatty acid is usually C16. However, in the mammary glands of non-ruminant mammals, and in the uropygial gland of certain waterfowl there exists a second thioesterase which releases medium-chain length fatty acids (C8 to C2) (By similarity).
-[[Category: Kridel, S.J]]
+__TOC__
+</StructureSection>
+[[Category: Kridel, S J]]
+[[Category: Lowther, W T]]
+[[Category: Ritchie, M K]]
+[[Category: Closed conformation]]
+[[Category: Fatty acid synthase]]
+[[Category: Hydrolase]]
+[[Category: Lipid metabolism]]