Defensin: Difference between revisions
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<StructureSection load='2pm4' size='350' side='right' caption='Human α-defensin 1 (PDB entry [[2pm4]])' scene=''> | |||
== Function == | |||
'''Defensins''' (DEF) are small cationic defense proteins active against bacteria, fungi and viruses. DEF contains 6-8 conserved cysteine residues. DEF binds to microbial cell membrane forming pores and thus allowing outflow of essential nutrients. | '''Defensins''' (DEF) are small cationic defense proteins active against bacteria, fungi and viruses. DEF contains 6-8 conserved cysteine residues. DEF binds to microbial cell membrane forming pores and thus allowing outflow of essential nutrients.<ref>PMID:11742345</ref> For details on plant DEF see [[Plant defensin]]. | ||
== Relevance == | |||
There is increase in α-DEF in chronic inflammations and several cancers. | |||
</StructureSection> | |||
==3D structures of defensin== | ==3D structures of defensin== | ||
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
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**[[2lr3]] – DEF – barrel medic – NMR<br /> | **[[2lr3]] – DEF – barrel medic – NMR<br /> | ||
}} | }} | ||
== References == | |||
<references/> | |||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
