4xdg: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
''' | ==Crystal Structure of Quinone Reductase II in complex with 2-(4-aminophenyl)-5-methoxy-1-oxy-indol-3-one molecule== | ||
<StructureSection load='4xdg' size='340' side='right' caption='[[4xdg]], [[Resolution|resolution]] 1.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4xdg]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XDG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XDG FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3ZU:(2S)-2-(4-AMINOPHENYL)-1-HYDROXY-5-METHOXY-1,2-DIHYDRO-3H-INDOL-3-ONE'>3ZU</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribosyldihydronicotinamide_dehydrogenase_(quinone) Ribosyldihydronicotinamide dehydrogenase (quinone)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.99.2 1.10.99.2] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xdg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xdg OCA], [http://pdbe.org/4xdg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xdg RCSB], [http://www.ebi.ac.uk/pdbsum/4xdg PDBsum]</span></td></tr> | |||
[[Category: | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/NQO2_HUMAN NQO2_HUMAN]] The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.<ref>PMID:18254726</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Boutin, J A]] | |||
[[Category: Ferry, G]] | [[Category: Ferry, G]] | ||
[[Category: | [[Category: Isabet, T]] | ||
[[Category: Nepveu, F]] | [[Category: Nepveu, F]] | ||
[[Category: Sirigu, S]] | [[Category: Sirigu, S]] | ||
[[Category: | [[Category: Thompson, A]] | ||
[[Category: Vuillard, L]] | [[Category: Vuillard, L]] | ||
[[Category: | [[Category: Fad]] | ||
[[Category: Flavoprotein]] | |||
[[Category: Indolone oxide]] | |||
[[Category: Metal-binding]] | |||
[[Category: Oxidoreductase]] | |||
[[Category: Qr2]] | |||
Revision as of 20:22, 13 January 2016
Crystal Structure of Quinone Reductase II in complex with 2-(4-aminophenyl)-5-methoxy-1-oxy-indol-3-one molecule
| ||||||||||||
