Exonuclease: Difference between revisions
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<StructureSection load='1fxx' size='350' side='right' scene='' caption='E. coli exonuclease I complex with phosphate, glycerol and Mg+2 ion (PDB code [[1fxx]]) '> | |||
'''Exonucleases''' (ExN) cleave nucleotides at the end of a polynucleotide chain. In E. coli there are ExN I to VIII.<br /> | |||
'''Exonucleases''' (ExN) cleave nucleotides at the end of a polynucleotide chain<ref>PMID:8747466</ref>. In ''E. coli'' there are ExN I to VIII.<br /> | |||
* '''ExN-I''' cleaves single-stranded DNA.<br /> | * '''ExN-I''' cleaves single-stranded DNA.<br /> | ||
* '''ExN-II''' is associated with DNA polymerase.<br /> | * '''ExN-II''' is associated with DNA polymerase.<br /> | ||
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* '''ExN-VIII''' requires a free 5’ OH group for reacting.<br /> | * '''ExN-VIII''' requires a free 5’ OH group for reacting.<br /> | ||
* '''ExN''' were found in human and yeast as well. | * '''ExN''' were found in human and yeast as well. | ||
</StructureSection> | |||
== 3D Structures of exonuclease == | == 3D Structures of exonuclease == | ||
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}} | }} | ||
== References == | |||
<references/> | |||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
