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| {{STRUCTURE_2bmv| PDB=2bmv | SIZE=300| SCENE=Flavodoxin/Cv/1 |right|CAPTION=Apo-Flavodoxin from ''Helicobacter pylori'' complexed with benzamidine and chloride ion, [[2bmv]] }}
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| [[Flavodoxin]] (FDX) is a bacterial protein which contains flavin mononucleotide (FMN) or flavin adenine dinucleotide (FAD). It participates in nitrogen metabolism and reduces N2 to NH3 while changing from its oxidized quinone state FDX-ox via semiquinone FDX-sq to its reduced hydroquinone state FDX-red. '''NrdI''' is a FDX which is involved in ribonucleotide reduction. '''WrbA (Tryptophan Repressor-Binding Protein)''' is also FDX. In ''E. coli'' there are 2 distinct FDX I and II. The space filling objects are of chloride ion and benzamidine. | | <StructureSection load='2bmv' size='350' side='right' scene='' caption='Apo-Flavodoxin from ''Helicobacter pylori'' complexed with benzamidine and chloride ion (PDB code [[2bmv]]) '> |
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| | [[Flavodoxin]] (FDX) is a bacterial protein which contains flavin mononucleotide (FMN) or flavin adenine dinucleotide (FAD). It participates in nitrogen metabolism and reduces N2 to NH3 while changing from its oxidized quinone state FDX-ox via semiquinone FDX-sq to its reduced hydroquinone state FDX-red<ref>PMID:8747466</ref>. '''NrdI''' is a FDX which is involved in ribonucleotide reduction. '''WrbA (Tryptophan Repressor-Binding Protein)''' is also FDX. In ''E. coli'' there are 2 distinct flavodoxins: FDX I and II. |
| | </StructureSection> |
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| == 3D Structures of Flavodoxin == | | == 3D Structures of Flavodoxin == |
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| **[[1j8q]] - DvFDX<br /> | | **[[1j8q]] - DvFDX<br /> |
| }} | | }} |
| | == References == |
| | <references/> |
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| [[Category:Topic Page]] | | [[Category:Topic Page]] |
Revision as of 17:46, 22 January 2016
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Flavodoxin (FDX) is a bacterial protein which contains flavin mononucleotide (FMN) or flavin adenine dinucleotide (FAD). It participates in nitrogen metabolism and reduces N2 to NH3 while changing from its oxidized quinone state FDX-ox via semiquinone FDX-sq to its reduced hydroquinone state FDX-red[1]. NrdI is a FDX which is involved in ribonucleotide reduction. WrbA (Tryptophan Repressor-Binding Protein) is also FDX. In E. coli there are 2 distinct flavodoxins: FDX I and II.
- ↑ Athappilly FK, Hendrickson WA. Structure of the biotinyl domain of acetyl-coenzyme A carboxylase determined by MAD phasing. Structure. 1995 Dec 15;3(12):1407-19. PMID:8747466
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3D Structures of Flavodoxin
Updated on 22-January-2016
{"openlevels":0}
- Apo FDX
- 2kqu, 1dx9 – AnFDX (mutant) apo – Anabanea – NMR
- 2bmv – HpFDX apo - Helicobacter pylori
- 3d7n – FDX apo – Agrobacterium tumefaciens
- 2rg1 - EcFDX WrbA apo - Escherichia coli
- 2hna, 2hnb, 2m6r, 2m6s – EcFDX apo – NMR
- 1qhe, 1ftg – nFDX apo – Nostoc
- 1bu5 – DvFDX apo+riboflavin - Desulfovibrio vulgaris
- FDX containing FMN oxidized (quinone)
- 3f6r, 3f6s, 3kap – DdFDX-ox - Desulfovibrio desulfuricans
- 4heq - FDX-ox – Desulfovibrio gigas
- 1ag9 – EcFDX-ox
- 1flv – nFDX-ox
- 1xyy, 1j9g, 1c7f, 1akr, 1akt, 1akw – DvFDX-ox (mutant)
- 2fx2, 3fx2, 4fx2, 5fx2, 1fx1 – DvFDX-ox
- 1czk, 1czr – SeFDX-ox (mutant) - Synechococcus elongates
- 1czn – SeFDX-ox I
- 1ofv – SeFDX-ox II
- 1czu, 1d03 - SeFDX-ox II
- 2fdx, 1fld, 1fvx, 2fax, 3nll, 4nll, 4nul, 5nll – CbFDX-ox (mutant) - Clostridium beijerinckii
- 2fcr – FDX-ox – Chondrus crispus
- 1fue – HpFDX-ox
- 4j8p - FDX-ox – Bacterioides uniformis
- 1i1o - DvFDX-ox
- FDX containing FMNH (semiquinone)
- FDX containing FMNH2 (hydroquinone)
- Other FDX
- 3esx, 3esy, 3esz, 2v5u, 2v5v, 1obo, 1obv - AnFDX (mutant)
- 1rcf, 1flv - AnFDX
- 2wc1 – FDX – Rhodobacter capsulatus
- 2w5u – HpFDX+C3 inhibitor 1fue - HpFDX
- 2kaq – DdFDX
- 2r97, 2r96 – EcFDX WrbA
- 1ahn – EcFDX
- 2q9u – FDX di-iron – Giardia intestinalis
- 2ark – FDX – Aquifex aeolicus
- 1yob – FDX II – Azotobacter vinelandii
- 1j9e, 1f4p, 1i10, 1azl – DvFDX (mutant)
- 1j8q - DvFDX
References
