Sandbox Reserved 1134: Difference between revisions
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MCP1 is part of the C-C motif group because of the covalent bond made between <scene name='72/721520/Cv/4'>2 of the 4 cysteines of the N terminal domain</scene>.<ref>PMID:8989326</ref> | MCP1 is part of the C-C motif group because of the covalent bond made between <scene name='72/721520/Cv/4'>2 of the 4 cysteines of the N terminal domain</scene>.<ref>PMID:8989326</ref> | ||
Post translational modifications at the N-terminus can regulate receptor and target cell selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant. | Post translational modifications at the N-terminus can regulate receptor and target cell selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant. | ||
== Synthesis == | == Synthesis == | ||
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MCP1 was crystallized and the structure was determined by X-ray diffraction at 1.9-A resolution. | MCP1 was crystallized and the structure was determined by X-ray diffraction at 1.9-A resolution. | ||
</StructureSection> | |||
[[Image:chaine.png]] | |||
== References == | == References == | ||
https://fr.wikipedia.org/wiki/CCL2 | https://fr.wikipedia.org/wiki/CCL2 | ||
