Sandbox Reserved 1121: Difference between revisions
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== Human C-reactive protein complexed with phosphocholine == | == Human C-reactive protein complexed with phosphocholine == | ||
Human C-Reactive Protein (CRP) is an acute phase protein belonging to the highly conserved pentraxin protein family <ref name="Thompson">PMID: 10368284</ref>. Although it is a normal serum protein, its circulating concentration raises rapidly and extensively in a cytokine-mediated in response to an infection, an inflammation or a tissue injury. In this way, serum CRP rate is empirically dose to detect many human disease <ref name="Thompson"/>. | Human C-Reactive Protein (CRP) is an acute phase protein belonging to the highly conserved pentraxin protein family, like as its homologue, the Serum Amyloid P component (SAP) <ref name="Thompson">PMID: 10368284</ref>. Although it is a normal serum protein, its circulating concentration raises rapidly and extensively in a cytokine-mediated in response to an infection, an inflammation or a tissue injury. In this way, serum CRP rate is empirically dose to detect many human disease <ref name="Thompson"/>. CRP was named this way because it was found that the protein could precipitate the "C" polysaccharide derived from Streptococcus pneumoniae cell wall <ref>PMID: 15337754</ref>. | ||
