Sandbox Reserved 1120: Difference between revisions
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<StructureSection load='1hry' size='340' side='right' caption='The SRY protein linked to DNA' scene=''> | <StructureSection load='1hry' size='340' side='right' caption='The SRY protein linked to DNA' scene=''> | ||
The SRY protein is a 204 residues long monomeric polypeptide | The SRY protein is a 204 residues long monomeric polypeptide. It is a '''transcriptionnal factor''', It activates the '''M'''üllerian '''I'''nhibiting '''S'''ubstance ('''MIS''' gene). | ||
It is encoded by the [[testis-determining sex gene]] and is itself involved in the sex determination in mammels by being responsible for the gonadogenesis thus the male sexual developement. It is the HMG-box that gives to the protein its ability to | It is encoded by the [[testis-determining sex gene]] and is itself involved in the sex determination in mammels by being responsible for the gonadogenesis thus the male sexual developement. It is the HMG-box that gives to the protein its ability to bind DNA by its minor groove. <ref>PMID: 9626701</ref> | ||
