4xuj: Difference between revisions

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'''Unreleased structure'''
==X-ray structure of NCP containing RuII-arene complex of thiomorpholine substituted 3-Hydroxy-2-pyridone ligands==
 
<StructureSection load='4xuj' size='340' side='right' caption='[[4xuj]], [[Resolution|resolution]] 3.18&Aring;' scene=''>
The entry 4xuj is ON HOLD  until Paper Publication
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4xuj]] is a 10 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XUJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XUJ FirstGlance]. <br>
Authors: Adhireksan, Z., Davey, C.A.
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4A6:[(1,2,3,4,5,6-ETA)-1-METHYL-4-(PROPAN-2-YL)BENZENE]RUTHENIUM'>4A6</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xuj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xuj OCA], [http://pdbe.org/4xuj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xuj RCSB], [http://www.ebi.ac.uk/pdbsum/4xuj PDBsum]</span></td></tr>
Description: X-ray structure of NCP containing RuII-arene complex of thiomorpholine substituted 3-Hydroxy-2-pyridone ligands
</table>
[[Category: Unreleased Structures]]
== Function ==
[[http://www.uniprot.org/uniprot/H2B11_XENLA H2B11_XENLA]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [[http://www.uniprot.org/uniprot/H32_XENLA H32_XENLA]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [[http://www.uniprot.org/uniprot/H4_XENLA H4_XENLA]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
__TOC__
</StructureSection>
[[Category: Adhireksan, Z]]
[[Category: Adhireksan, Z]]
[[Category: Davey, C.A]]
[[Category: Davey, C A]]
[[Category: Dna-bindig protein-dna complex]]
[[Category: Dna-binding protein-dna complex]]
[[Category: Nucleosome]]
[[Category: Ruthenium agent]]
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