2cb2: Difference between revisions
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==Overview== | ==Overview== | ||
Numerous microorganisms oxidize sulfur for energy conservation and, contribute to the global biogeochemical sulfur cycle. We have determined, the 1.7 angstrom-resolution structure of the sulfur oxygenase reductase, from the thermoacidophilic archaeon Acidianus ambivalens, which catalyzes, an oxygen-dependent disproportionation of elemental sulfur. Twenty-four, monomers form a large hollow sphere enclosing a positively charged, nanocompartment. Apolar channels provide access for linear sulfur species., A cysteine persulfide and a low-potential mononuclear non-heme iron site, ligated by a 2-His-1-carboxylate facial triad in a pocket of each subunit, constitute the active sites, accessible from the inside of the sphere. The, iron is likely the site of both sulfur oxidation and sulfur . | Numerous microorganisms oxidize sulfur for energy conservation and, contribute to the global biogeochemical sulfur cycle. We have determined, the 1.7 angstrom-resolution structure of the sulfur oxygenase reductase, from the thermoacidophilic archaeon Acidianus ambivalens, which catalyzes, an oxygen-dependent disproportionation of elemental sulfur. Twenty-four, monomers form a large hollow sphere enclosing a positively charged, nanocompartment. Apolar channels provide access for linear sulfur species., A cysteine persulfide and a low-potential mononuclear non-heme iron site, ligated by a 2-His-1-carboxylate facial triad in a pocket of each subunit, constitute the active sites, accessible from the inside of the sphere. The, iron is likely the site of both sulfur oxidation and sulfur reduction. | ||
==About this Structure== | ==About this Structure== | ||
2CB2 is a | 2CB2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Acidianus_ambivalens Acidianus ambivalens] with FE as [http://en.wikipedia.org/wiki/ligand ligand]. Structure known Active Site: AC1. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2CB2 OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: thermophilic]] | [[Category: thermophilic]] | ||
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 5 15:08:41 2007'' | ||
