Sandbox Reserved 1123: Difference between revisions

From Proteopedia
Jump to navigationJump to search
No edit summary
No edit summary
Line 34: Line 34:
== Capsid as therapeutical target ==
== Capsid as therapeutical target ==


<Structure load='2XDE' size='300' frame='false' align='left' caption='Cristal structure of PF-3450074 with N terminal domain of HIV capsid PDB:2XDE' scene='Insert optional scene name here' />'
<Structure load='2XDE' size='400' frame='false' align='left' caption='Cristal structure of PF-3450074 with N terminal domain of HIV capsid PDB:2XDE' scene='71/719864/Hiv_dimer_with_ligand/1' />'


Thank to its central role in viral infectious process (genome protection, enveloppe cohesion, uncoating, budding), HIV capsid is a very good target for antiviral drugs. As a result, many research teams are working in this way and some molecules such as PF-3450074 <ref name="A"/> are very promising.  
Thank to its central role in viral infectious process (genome protection, enveloppe cohesion, uncoating, budding), HIV capsid is a very good target for antiviral drugs. As a result, many research teams are working in this way and some molecules such as PF-3450074 <ref name="A"/> are very promising.