Sandbox Reserved 1123: Difference between revisions
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== Capsid as therapeutical target == | == Capsid as therapeutical target == | ||
<Structure load='2XDE' size=' | <Structure load='2XDE' size='400' frame='false' align='left' caption='Cristal structure of PF-3450074 with N terminal domain of HIV capsid PDB:2XDE' scene='71/719864/Hiv_dimer_with_ligand/1' />' | ||
Thank to its central role in viral infectious process (genome protection, enveloppe cohesion, uncoating, budding), HIV capsid is a very good target for antiviral drugs. As a result, many research teams are working in this way and some molecules such as PF-3450074 <ref name="A"/> are very promising. | Thank to its central role in viral infectious process (genome protection, enveloppe cohesion, uncoating, budding), HIV capsid is a very good target for antiviral drugs. As a result, many research teams are working in this way and some molecules such as PF-3450074 <ref name="A"/> are very promising. | ||