Sandbox Reserved 1120: Difference between revisions
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Because the human's SRY organisation is very closed to he mouse's, it has been proposed that SRY would have the same function in human but it has not been studied directly.<ref>PMID:22315667</ref> | Because the human's SRY organisation is very closed to he mouse's, it has been proposed that SRY would have the same function in human but it has not been studied directly.<ref>PMID:22315667</ref> | ||
===Cathecolamines | ===Cathecolamines regulation=== | ||
It has been shown SRY is present in brain regions and activate the Tyrosine-3-Hydroxylase expression. This enzyme catalyses the rate-limiting step of catecholamine synthesis (L-Tyrosine to L-DOPA). Furthermore, SRY also activate the expression of Monoamine Oxidase A which is responsible for the inactivation of catecholamines. Therefore, it regulates both positively and negatively the catecholamines concentration. | |||