1e2k: Difference between revisions
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|PDB= 1e2k |SIZE=350|CAPTION= <scene name='initialview01'>1e2k</scene>, resolution 1.7Å | |PDB= 1e2k |SIZE=350|CAPTION= <scene name='initialview01'>1e2k</scene>, resolution 1.7Å | ||
|SITE= <scene name='pdbsite=AC1:Tmc+Binding+Site+For+Chain+A'>AC1</scene> and <scene name='pdbsite=AC2:Tmc+Binding+Site+For+Chain+B+Symmetry+Related+Subunits+C+...'>AC2</scene> | |SITE= <scene name='pdbsite=AC1:Tmc+Binding+Site+For+Chain+A'>AC1</scene> and <scene name='pdbsite=AC2:Tmc+Binding+Site+For+Chain+B+Symmetry+Related+Subunits+C+...'>AC2</scene> | ||
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> | |LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TMC:1-[4-HYDROXY-5-(HYDROXYMETHYL)BICYCLO[3.1.0]HEX-2-YL]-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE'>TMC</scene> | ||
|ACTIVITY= [http://en.wikipedia.org/wiki/Thymidine_kinase Thymidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.21 2.7.1.21] | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidine_kinase Thymidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.21 2.7.1.21] </span> | ||
|GENE= | |GENE= | ||
|DOMAIN= | |||
|RELATEDENTRY= | |||
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1e2k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e2k OCA], [http://www.ebi.ac.uk/pdbsum/1e2k PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1e2k RCSB]</span> | |||
}} | }} | ||
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==About this Structure== | ==About this Structure== | ||
1E2K is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/ | 1E2K is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_herpesvirus_1 Human herpesvirus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E2K OCA]. | ||
==Reference== | ==Reference== | ||
Kinetics and crystal structure of the wild-type and the engineered Y101F mutant of Herpes simplex virus type 1 thymidine kinase interacting with (North)-methanocarba-thymidine., Prota A, Vogt J, Pilger B, Perozzo R, Wurth C, Marquez VE, Russ P, Schulz GE, Folkers G, Scapozza L, Biochemistry. 2000 Aug 8;39(31):9597-603. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10924157 10924157] | Kinetics and crystal structure of the wild-type and the engineered Y101F mutant of Herpes simplex virus type 1 thymidine kinase interacting with (North)-methanocarba-thymidine., Prota A, Vogt J, Pilger B, Perozzo R, Wurth C, Marquez VE, Russ P, Schulz GE, Folkers G, Scapozza L, Biochemistry. 2000 Aug 8;39(31):9597-603. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10924157 10924157] | ||
[[Category: Human herpesvirus | [[Category: Human herpesvirus 1]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Thymidine kinase]] | [[Category: Thymidine kinase]] | ||
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[[Category: Schulz, G E.]] | [[Category: Schulz, G E.]] | ||
[[Category: Vogt, J.]] | [[Category: Vogt, J.]] | ||
[[Category: antiviral drug]] | [[Category: antiviral drug]] | ||
[[Category: enzyme-prodrug gene therapy]] | [[Category: enzyme-prodrug gene therapy]] | ||
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[[Category: x-ray structure]] | [[Category: x-ray structure]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:53:42 2008'' | ||
