4wre: Difference between revisions
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''' | ==Crystal Structure of Surfactant Protein-A DEDN Mutant (E171D/P175E/R197N/K203D) Complexed with Inositol== | ||
<StructureSection load='4wre' size='340' side='right' caption='[[4wre]], [[Resolution|resolution]] 1.75Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4wre]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WRE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WRE FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HEZ:HEXANE-1,6-DIOL'>HEZ</scene>, <scene name='pdbligand=INS:1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE'>INS</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wr9|4wr9]], [[4wrc|4wrc]], [[4wrf|4wrf]]</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wre FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wre OCA], [http://pdbe.org/4wre PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wre RCSB], [http://www.ebi.ac.uk/pdbsum/4wre PDBsum]</span></td></tr> | |||
[[Category: | </table> | ||
[[Category: Head, J | == Function == | ||
[[Category: | [[http://www.uniprot.org/uniprot/SFTPA_RAT SFTPA_RAT]] In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Cafarella, T R]] | ||
[[Category: Head, J F]] | |||
[[Category: McCormack, F X]] | |||
[[Category: Nikolaidis, N M]] | |||
[[Category: Rynkiewicz, M J]] | |||
[[Category: Seaton, B A]] | |||
[[Category: Wu, H]] | [[Category: Wu, H]] | ||
[[Category: | [[Category: Carbohydrate binding]] | ||
[[Category: Collectin]] | |||
[[Category: Lectin]] | |||
[[Category: Lipid binding]] | |||
[[Category: Sugar binding protein]] | |||
Revision as of 17:20, 10 February 2016
Crystal Structure of Surfactant Protein-A DEDN Mutant (E171D/P175E/R197N/K203D) Complexed with Inositol
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