4y0i: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 4y0i ~~is ON HOLD until Paper Publication~~

==GABA-aminotransferase inactivated by conformationally-restricted inactivator==

~~Authors~~: ~~Wu, R~~., ~~Sanishvili~~, R., ~~Lee, H~~.V., ~~Dustin~~, D.H., ~~Emma, D~~.~~, Neil, K~~., ~~Silverman, R~~.B., ~~Liu~~, D.

== Structural highlights ==

<table><tr><td colspan='2'>[[4y0i]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y0I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y0I FirstGlance]. <br>

~~Description~~: ~~GABA-aminotransferase inactivated by conformationally-restricted inactivator~~

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PSZ:4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]THIOPHENE-2-CARBOXYLIC+ACID'>PSZ</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y0i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y0i OCA], [http://pdbe.org/4y0i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y0i RCSB], [http://www.ebi.ac.uk/pdbsum/4y0i PDBsum]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/GABT_PIG GABT_PIG]] Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine.

__TOC__

</StructureSection>

[[Category: Dustin, D H]]

[[Category: Emma, D]]

[[Category: Lee, H V]]

[[Category: Liu, D]]

[[Category: Neil, K]]

[[Category: Sanishvili, R]]

[[Category: ~~Neil~~, ~~K]]~~

[[Category: Silverman, R B]]

~~[[Category: Liu, D~~]]

[[Category: Wu, R]]

[[Category: ~~Dustin, D.H~~]]

[[Category: Biological evaluation]]

[[Category: ~~Emma, D~~]]

[[Category: Mechanistic studies of con-formationally-restricted gaba-aminotransferase inactivator]]

[[Category: ~~Silverman, R.B~~]]

[[Category: Synthesis]]

[[Category: ~~Lee, H.V~~]]

[[Category: Transferase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 4y0i is ON HOLD  until Paper Publication
+==GABA-aminotransferase inactivated by conformationally-restricted inactivator==
+<StructureSection load='4y0i' size='340' side='right' caption='[[4y0i]], [[Resolution|resolution]] 1.66&Aring;' scene=''>
-Authors: Wu, R., Sanishvili, R., Lee, H.V., Dustin, D.H., Emma, D., Neil, K., Silverman, R.B., Liu, D.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4y0i]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y0I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y0I FirstGlance]. <br>
-Description: GABA-aminotransferase inactivated by conformationally-restricted inactivator
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PSZ:4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]THIOPHENE-2-CARBOXYLIC+ACID'>PSZ</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y0i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y0i OCA], [http://pdbe.org/4y0i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y0i RCSB], [http://www.ebi.ac.uk/pdbsum/4y0i PDBsum]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/GABT_PIG GABT_PIG]] Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine.
+__TOC__
+</StructureSection>
+[[Category: Dustin, D H]]
+[[Category: Emma, D]]
+[[Category: Lee, H V]]
+[[Category: Liu, D]]
+[[Category: Neil, K]]
 [[Category: Sanishvili, R]]
-[[Category: Neil, K]]
+[[Category: Silverman, R B]]
-[[Category: Liu, D]]
 [[Category: Wu, R]]
-[[Category: Dustin, D.H]]
+[[Category: Biological evaluation]]
-[[Category: Emma, D]]
+[[Category: Mechanistic studies of con-formationally-restricted gaba-aminotransferase inactivator]]
-[[Category: Silverman, R.B]]
+[[Category: Synthesis]]
-[[Category: Lee, H.V]]
+[[Category: Transferase]]