5cz2: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5cz2 is ~~ON HOLD until Paper Publication~~

==Crystal structure of a two-domain fragment of MMTV integrase==

~~Authors~~: ~~Cook~~, N.~~, Ballandras~~-~~Colas~~, A., ~~Engelman~~, A.~~, Cherepanov, P~~.

== Structural highlights ==

<table><tr><td colspan='2'>[[5cz2]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CZ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CZ2 FirstGlance]. <br>

~~Description: Crystal structure of a two-domain fragment MMTV integrase~~

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

[[~~Category~~: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cz2 OCA], [http://pdbe.org/5cz2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cz2 RCSB], [http://www.ebi.ac.uk/pdbsum/5cz2 PDBsum]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/POL_MMTVB POL_MMTVB]] During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme. RNase H activity is associated with the reverse transcriptase.

__TOC__

</StructureSection>

[[Category: Ballandras-Colas, A]]

[[Category: Cherepanov, P]]

[[Category: Cook, N]]

[[Category: Engelman, A]]

[[Category: ~~Cherepanov, P~~]]

[[Category: Amino terminal domain]]

[[Category: Catalytic core domain]]

[[Category: Hydrolase]]

[[Category: Integrase]]

[[Category: Pol]]

[[Category: Retrovirus]]

[[Category: Zinc binding]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5cz2 is ON HOLD  until Paper Publication
+==Crystal structure of a two-domain fragment of MMTV integrase==
+<StructureSection load='5cz2' size='340' side='right' caption='[[5cz2]], [[Resolution|resolution]] 2.72&Aring;' scene=''>
-Authors: Cook, N., Ballandras-Colas, A., Engelman, A., Cherepanov, P.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5cz2]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CZ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CZ2 FirstGlance]. <br>
-Description: Crystal structure of a two-domain fragment MMTV integrase
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cz2 OCA], [http://pdbe.org/5cz2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cz2 RCSB], [http://www.ebi.ac.uk/pdbsum/5cz2 PDBsum]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/POL_MMTVB POL_MMTVB]] During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme. RNase H activity is associated with the reverse transcriptase.
+__TOC__
+</StructureSection>
 [[Category: Ballandras-Colas, A]]
+[[Category: Cherepanov, P]]
 [[Category: Cook, N]]
 [[Category: Engelman, A]]
-[[Category: Cherepanov, P]]
+[[Category: Amino terminal domain]]
+[[Category: Catalytic core domain]]
+[[Category: Hydrolase]]
+[[Category: Integrase]]
+[[Category: Pol]]
+[[Category: Retrovirus]]
+[[Category: Zinc binding]]