5eak: Difference between revisions
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==Optimization of Microtubule Affinity Regulating Kinase (MARK) Inhibitors with Improved Physical Properties== | |||
<StructureSection load='5eak' size='340' side='right' caption='[[5eak]], [[Resolution|resolution]] 2.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5eak]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EAK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EAK FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=24R:N-[(1S,2R)-2-AMINOCYCLOHEXYL]-4-[6-(1-METHYL-1H-PYRAZOL-4-YL)PYRAZOLO[1,5-A]PYRIMIDIN-3-YL]THIOPHENE-2-CARBOXAMIDE'>24R</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5eak FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eak OCA], [http://pdbe.org/5eak PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5eak RCSB], [http://www.ebi.ac.uk/pdbsum/5eak PDBsum]</span></td></tr> | ||
[[Category: | </table> | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Su, H P]] | |||
[[Category: Catalytic domain]] | |||
[[Category: Kinase inhibitor]] | |||
[[Category: Protein-serine-threonine kinase]] | |||
[[Category: Serine-threonine kinase]] | |||
[[Category: Transferase-transferase inhibitor complex]] | |||
Revision as of 02:54, 21 February 2016
Optimization of Microtubule Affinity Regulating Kinase (MARK) Inhibitors with Improved Physical Properties
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