Sandbox Reserved 427: Difference between revisions
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==Binding Interactions== | ==Binding Interactions== | ||
'''The Vitamin D Binding Site''' | |||
Describe the chemical make-up of the binding. Talk about hydrophobic interactions with vitamin D3 ligands. Hydrogen bond formation with 250HD3. Also discuss steric strain and binding affinity. | |||
'''Biological Relevance of The Vitamin D Binding Site''' | |||
Vitamin D hormone 1,25(OH)2D3 used to treat renal osteodystrophy, hypoparathyroidism and osteoporosis. Discuss selectivity and binding affinity of synthesized molecules | |||
<Structure load='1j7e' size='300' frame='true' align='right' caption='1j7e, Insert caption here' scene='Insert optional scene name here' /> | <Structure load='1j7e' size='300' frame='true' align='right' caption='1j7e, Insert caption here' scene='Insert optional scene name here' /> | ||
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