Transfer RNA tour: Difference between revisions

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==A-form RNA==

Source <ref>PMID:~~77038371~~</ref>

Source <ref>PMID:790568</ref>

== Structural highlights ==

===Domains===

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[[Image:JnTerts.GIF]]

<scene name='72/725890/Trna_tert_interact/2'>You can zoom in for a closer look</scene>. The yellow residues are a parallel base pair (compared to the normal anti parallel) between G15 of the D-loop and C48 of the variable loop. This brings the D-loop and variable loop together. Note the sharp turn in the backbone between C48 and C49 caused by the parallel pair.~~~~

<scene name='72/725890/Trna_tert_interact/2'>You can zoom in for a closer look</scene>. The yellow residues are a parallel base pair (compared to the normal anti parallel) between G15 of the D-loop and C48 of the variable loop. This brings the D-loop and variable loop together. Note the sharp turn in the backbone between C48 and C49 caused by the parallel pair.

The green residues are a reverse Hoogsteen pair between U8and A14. This pairing is important for positioning of the D stem relative to the stacked T and acceptor stems.~~~~

The green residues are a reverse Hoogsteen pair between U8and A14. This pairing is important for positioning of the D stem relative to the stacked T and acceptor stems.

The cyan residues are a base triple in which A9H-bonds in the major groove to A23 (which is paired with U12). It stabilizes a sharp turn between bases 9 and 10.~~~~

The cyan residues are a base triple in which A9H-bonds in the major groove to A23 (which is paired with U12). It stabilizes a sharp turn between bases 9 and 10.

The red residues are a base triple in which 7-methyl-G46 from the variable loop H-bonds to the G22-C13 base pair of the D stem. This helps dock the variable loop onto the D-stem.~~~~

The red residues are a base triple in which 7-methyl-G46 from the variable loop H-bonds to the G22-C13 base pair of the D stem. This helps dock the variable loop onto the D-stem.

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@@ Line 1: / Line 1: @@
 ==A-form RNA==
 <StructureSection load='1tra' size='400' side='right' caption='phe-tRNA [[1tra]]' scene='72/725890/Trna_overview/1'>
-Source <ref>PMID:77038371</ref>
+Source <ref>PMID:790568</ref>
 == Structural highlights ==
 ===Domains===
@@ Line 15: / Line 15: @@
 [[Image:JnTerts.GIF]]
-<scene name='72/725890/Trna_tert_interact/2'>You can zoom in for a closer look</scene>. The yellow residues are a parallel base pair (compared to the normal anti parallel) between <B><FONT COLOR="#aaaa00">G15</FONT></B> of the <B>D-loop</B> and <B><FONT COLOR="#aaaa00">C48</FONT></B> of the <B>variable loop</B>. This brings the <B>D-loop</B> and <B>variable loop</B> together. Note the sharp turn in the backbone between <B><FONT COLOR="#ffff00">C48</FONT></B> and <B><FONT COLOR="#ffff00">C49</FONT></B> caused by the parallel pair.</P>
+<scene name='72/725890/Trna_tert_interact/2'>You can zoom in for a closer look</scene>. The yellow residues are a parallel base pair (compared to the normal anti parallel) between <B><FONT COLOR="#aaaa00">G15</FONT></B> of the <B>D-loop</B> and <B><FONT COLOR="#aaaa00">C48</FONT></B> of the <B>variable loop</B>. This brings the <B>D-loop</B> and <B>variable loop</B> together. Note the sharp turn in the backbone between <B><FONT COLOR="#ffff00">C48</FONT></B> and <B><FONT COLOR="#ffff00">C49</FONT></B> caused by the parallel pair.
-The green residues are a reverse Hoogsteen pair between <B><FONT COLOR="#00bf00">U8</FONT></B>and <B><FONT COLOR="#00bf00">A14</FONT></B>. This pairing is important for positioning of the <B>D stem</B> relative to the stacked <B>T</B> and <B>acceptor</B> stems.</P>
+The green residues are a reverse Hoogsteen pair between <B><FONT COLOR="#00bf00">U8</FONT></B>and <B><FONT COLOR="#00bf00">A14</FONT></B>. This pairing is important for positioning of the <B>D stem</B> relative to the stacked <B>T</B> and <B>acceptor</B> stems.
-The cyan residues are a base triple in which <B><FONT COLOR="#008aff">A9</FONT></B>H-bonds in the major groove to <B><FONT COLOR="#008aff">A23</FONT></B> (which is paired with <B><FONT COLOR="#008aff">U12</FONT></B>). It stabilizes a sharp turn between bases 9 and 10.</P>
+The cyan residues are a base triple in which <B><FONT COLOR="#008aff">A9</FONT></B>H-bonds in the major groove to <B><FONT COLOR="#008aff">A23</FONT></B> (which is paired with <B><FONT COLOR="#008aff">U12</FONT></B>). It stabilizes a sharp turn between bases 9 and 10.
-The red residues are a base triple in which <B><FONT COLOR="#ff0000">7-methyl-G46</FONT></B> from the <B>variable loop</B> H-bonds to the <B><FONT COLOR="#ff0000">G22-C13</FONT></B> base pair of the <B>D stem</B>. This helps dock the <B>variable loop</B> onto the <B>D-stem</B>.</P>
+The red residues are a base triple in which <B><FONT COLOR="#ff0000">7-methyl-G46</FONT></B> from the <B>variable loop</B> H-bonds to the <B><FONT COLOR="#ff0000">G22-C13</FONT></B> base pair of the <B>D stem</B>. This helps dock the <B>variable loop</B> onto the <B>D-stem</B>.