5f41: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5f41 is ~~ON HOLD until Paper Publication~~

==DENGUE SEROTYPE 3 RNA-DEPENDENT RNA POLYMERASE BOUND TO FD-83-KI26==

~~Authors~~: ~~Noble~~, C.G.

== Structural highlights ==

<table><tr><td colspan='2'>[[5f41]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F41 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5F41 FirstGlance].

~~Description:~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=5V6:2-(4-METHOXY-3-THIOPHEN-3-YL-PHENYL)ETHANOIC+ACID'>5V6</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

[[~~Category~~: ~~Unreleased Structures~~]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[5f3z|5f3z]], [[5fst|5fst]]</td></tr>

[[Category: Noble, C.G]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5f41 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f41 OCA], [http://pdbe.org/5f41 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5f41 RCSB], [http://www.ebi.ac.uk/pdbsum/5f41 PDBsum]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/Q6DLV0_9FLAV Q6DLV0_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS000336_004_099774]

__TOC__

</StructureSection>

[[Category: Noble, C G]]

[[Category: Dengue virus]]

[[Category: Inhibitor rdrp]]

[[Category: Transferase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5f41 is ON HOLD  until Paper Publication
+==DENGUE SEROTYPE 3 RNA-DEPENDENT RNA POLYMERASE BOUND TO FD-83-KI26==
+<StructureSection load='5f41' size='340' side='right' caption='[[5f41]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-Authors: Noble, C.G.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5f41]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F41 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5F41 FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5V6:2-(4-METHOXY-3-THIOPHEN-3-YL-PHENYL)ETHANOIC+ACID'>5V6</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5f3z|5f3z]], [[5fst|5fst]]</td></tr>
-[[Category: Noble, C.G]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5f41 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f41 OCA], [http://pdbe.org/5f41 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5f41 RCSB], [http://www.ebi.ac.uk/pdbsum/5f41 PDBsum]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/Q6DLV0_9FLAV Q6DLV0_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS000336_004_099774]
+__TOC__
+</StructureSection>
+[[Category: Noble, C G]]
+[[Category: Dengue virus]]
+[[Category: Inhibitor rdrp]]
+[[Category: Transferase]]