Transfer RNA tour: Difference between revisions

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[[Image:JnTerts.GIF]]
[[Image:JnTerts.GIF]]


<scene name='72/725890/Trna_tert_interact/2'>You can zoom in for a closer look</scene>. The yellow residues are a parallel base pair (compared to the normal anti parallel) between <B><FONT COLOR="#aaaa00">G15</FONT></B> of the <B>D-loop</B> and <B><FONT COLOR="#aaaa00">C48</FONT></B> of the <B>variable loop</B>. This brings the <B>D-loop</B> and <B>variable loop</B> together. Note the sharp turn in the backbone between <B><FONT COLOR="#aaaa00">C48</FONT></B> and <B><FONT COLOR="#aaaa00">C49</FONT></B> caused by the parallel pair.
<scene name='72/725890/Trna_tert_interact/3'>You can zoom in for a closer look</scene>. The yellow residues are a parallel base pair (compared to the normal anti parallel) between <B><FONT COLOR="#aaaa00">G15</FONT></B> of the <B>D-loop</B> and <B><FONT COLOR="#aaaa00">C48</FONT></B> of the <B>variable loop</B>. This brings the <B>D-loop</B> and <B>variable loop</B> together. Note the sharp turn in the backbone between <B><FONT COLOR="#aaaa00">C48</FONT></B> and <B><FONT COLOR="#aaaa00">C49</FONT></B> caused by the parallel pair.


The green residues are a reverse Hoogsteen pair between <B><FONT COLOR="#00bf00">U8</FONT></B> and <B><FONT COLOR="#00bf00">A14</FONT></B>. This pairing is important for positioning of the <B>D stem</B> relative to the stacked <B>T</B> and <B>acceptor</B> stems.
The cyan residues are a reverse Hoogsteen pair between <B><FONT COLOR="#008aff">U8</FONT></B> and <B><FONT COLOR="#008aff">A14</FONT></B>. This pairing is important for positioning of the <B>D stem</B> relative to the stacked <B>T</B> and <B>acceptor</B> stems.


The cyan residues are a base triple in which <B><FONT COLOR="#008aff">A9</FONT></B> H-bonds in the major groove to <B><FONT COLOR="#008aff">A23</FONT></B> (which is paired with <B><FONT COLOR="#008aff">U12</FONT></B>). It stabilizes a sharp turn between bases 9 and 10.
The green residues are a base triple in which <B><FONT COLOR="#00bf00">A9</FONT></B> H-bonds in the major groove to <B><FONT COLOR="#00bf00">A23</FONT></B> (which is paired with <B><FONT COLOR="#00bf00">U12</FONT></B>). It stabilizes a sharp turn between bases 9 and 10.


The red residues are a base triple in which <B><FONT COLOR="#ff0000">7-methyl-G46</FONT></B> from the <B>variable loop</B> H-bonds to the <B><FONT COLOR="#ff0000">G22-C13</FONT></B> base pair of the <B>D stem</B>. This helps dock the <B>variable loop</B> onto the <B>D-stem</B>.
The red residues are a base triple in which <B><FONT COLOR="#ff0000">7-methyl-G46</FONT></B> from the <B>variable loop</B> H-bonds to the <B><FONT COLOR="#ff0000">G22-C13</FONT></B> base pair of the <B>D stem</B>. This helps dock the <B>variable loop</B> onto the <B>D-stem</B>.