5e56: Difference between revisions
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==Crystal structure of mouse CTLA-4== | |||
<StructureSection load='5e56' size='340' side='right' caption='[[5e56]], [[Resolution|resolution]] 1.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5e56]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E56 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5E56 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1dqt|1dqt]], [[5e5m|5e5m]]</td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5e56 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e56 OCA], [http://pdbe.org/5e56 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5e56 RCSB], [http://www.ebi.ac.uk/pdbsum/5e56 PDBsum]</span></td></tr> | ||
[[Category: Fedorov, A | </table> | ||
[[Category: | == Function == | ||
[[Category: | [[http://www.uniprot.org/uniprot/CTLA4_MOUSE CTLA4_MOUSE]] Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28 (By similarity). | ||
[[Category: | __TOC__ | ||
</StructureSection> | |||
[[Category: Almo, S C]] | |||
[[Category: Bonanno, J B]] | |||
[[Category: Fedorov, A A]] | |||
[[Category: Fedorov, E V]] | |||
[[Category: SAMANTA, D]] | |||
[[Category: Ig-fold]] | |||
[[Category: Immune system]] | |||
[[Category: Immunoglobulin variable domain]] | |||
Revision as of 06:54, 2 March 2016
Crystal structure of mouse CTLA-4
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