GTP-binding protein: Difference between revisions

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[[Image:2nzj.png|left|200px|thumb|Crystal Structure of GTP-binding protein Rem1 tetramer complex with nucleotide [[2nzj]]]]

'''GTP-binding proteins''' or '''G proteins''' are transmitting signals outside the cell which cause changes within the cell. They act as molecular switches which are on when binding GTP and off when binding GDP. GTP-binding proteins belong to two families: heterotrimeric G proteins and small GTPases<ref>PMID:~~8528769~~</ref>. See details on GTP-binding protein LepA in [[LepA]].

'''GTP-binding proteins''' or '''G proteins''' are transmitting signals outside the cell which cause changes within the cell. They act as molecular switches which are on when binding GTP and off when binding GDP. GTP-binding proteins belong to two families: '''heterotrimeric G proteins'''<ref>PMID:14762218</ref> and '''small GTPases'''<ref>PMID:11152757</ref>. See details on GTP-binding protein LepA in [[LepA]].

<scene name='Template:GPCR3sn6/3sn6memrane/15'>An activated G protein-coupled receptor</scene> (human β-2 adrenergic receptor in blue ) in a complex with a heterotrimeric G protein (3 subunits:reddish to orange-brown) and hormone (gold) ([[3sn6]]), resolution 3.2Å. The boundaries of the membrane in which the GPCR sits are represented in light green.

GTP-binding protein: Difference between revisions

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 [[Image:2nzj.png|left|200px|thumb|Crystal Structure of GTP-binding protein Rem1 tetramer complex with nucleotide [[2nzj]]]]
 {{Clear}}
-'''GTP-binding proteins''' or '''G proteins''' are transmitting signals outside the cell which cause changes within the cell.  They act as molecular switches which are on when binding GTP and off when binding GDP. GTP-binding proteins belong to two families: heterotrimeric G proteins and small GTPases<ref>PMID:8528769</ref>.  See details on GTP-binding protein LepA in [[LepA]].
+'''GTP-binding proteins''' or '''G proteins''' are transmitting signals outside the cell which cause changes within the cell.  They act as molecular switches which are on when binding GTP and off when binding GDP. GTP-binding proteins belong to two families: '''heterotrimeric G proteins'''<ref>PMID:14762218</ref> and '''small GTPases'''<ref>PMID:11152757</ref>.  See details on GTP-binding protein LepA in [[LepA]].
 <scene name='Template:GPCR3sn6/3sn6memrane/15'>An activated G protein-coupled receptor</scene> (human β-2 adrenergic receptor in blue ) in a complex with a heterotrimeric G protein (3 subunits:reddish to orange-brown) and hormone (gold) ([[3sn6]]), resolution 3.2&Aring;. The boundaries of the membrane in which the GPCR sits are represented in light green.