GTP-binding protein: Difference between revisions
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<scene name='Template:GPCR3sn6/3sn6memrane/15'>An activated G protein-coupled receptor</scene> (human β-2 adrenergic receptor in blue ) in a complex with a heterotrimeric G protein (3 subunits:reddish to orange-brown) and hormone (gold) ([[3sn6]]), resolution 3.2Å. The boundaries of the membrane in which the GPCR sits are represented in light green. | <scene name='Template:GPCR3sn6/3sn6memrane/15'>An activated G protein-coupled receptor</scene> (human β-2 adrenergic receptor in blue ) in a complex with a heterotrimeric G protein (3 subunits:reddish to orange-brown) and hormone (gold) ([[3sn6]]), resolution 3.2Å. The boundaries of the membrane in which the GPCR sits are represented in light green. | ||
== Disease == | |||
Mutations in heterotrimeric α subunit were identified in endocrine tumors and in McCune-Albright syndrome<ref>PMID:11720871</ref>. | |||
== Structural highlights == | == Structural highlights == | ||
''E. coli'' small GTPase ERA binds GDP in a cavity formed by 3 highly conserved regions<ref>PMID:19706445</ref>. | ''E. coli'' small GTPase ERA binds GDP in a cavity formed by 3 highly conserved regions<ref>PMID:19706445</ref>. | ||
