GTP-binding protein: Difference between revisions
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<StructureSection load='3ieu' size=' | <StructureSection load='3ieu' size='450' side='right' scene='46/463251/Cv/2' caption='E. coli small GTP-binding protein ERA complex with GDP and sulfate (PDB code [[3ieu]])'> | ||
__TOC__ | __TOC__ | ||
== Function == | == Function == | ||
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Mutations in heterotrimeric G protein α subunit were identified in endocrine tumors and in McCune-Albright syndrome<ref>PMID:11720871</ref>. | Mutations in heterotrimeric G protein α subunit were identified in endocrine tumors and in McCune-Albright syndrome<ref>PMID:11720871</ref>. | ||
== Structural highlights == | == Structural highlights == | ||
''E. coli'' small GTPase ERA binds GDP in a cavity formed by 3 highly conserved regions<ref>PMID:19706445</ref>. | ''E. coli'' small GTPase ERA binds GDP in a cavity formed by <scene name='46/463251/Cv/3'>3 highly conserved regions G1, G4, G5</scene><ref>PMID:19706445</ref>. <scene name='46/463251/Cv/6'>GDP binding site</scene>. Water molecules shown as red spheres. | ||
</StructureSection> | </StructureSection> | ||
__NOTOC__ | __NOTOC__ | ||
