Sandbox Reserved 1176: Difference between revisions
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===Ligand Binding Pocket=== | ===Ligand Binding Pocket=== | ||
Near the top of the protein is the | Near the top of the protein is the | ||
<scene name='72/721547/Hydrophobic_binding_pocket/ | <scene name='72/721547/Hydrophobic_binding_pocket/2'>hydrophobic binding pocket</scene> | ||
This pocket is comprised of several key amino acid resides. The first reside is a Phenylalanine at position F358. The purpose of this amino acid is to take part in a network of hydrophobic stacking interactions. These interactions stabilize the Y324 and W321 residues. These are crucial interactions because the Y324 is the amino acid residue that directly interacts for the | This pocket is comprised of several key amino acid resides. The first reside is a Phenylalanine at position F358. The purpose of this amino acid is to take part in a network of hydrophobic stacking interactions. These interactions stabilize the Y324 and W321 residues. These are crucial interactions because the Y324 is the amino acid residue that directly interacts for the | ||
<scene name='72/721547/Ligand_protein_interactions/3'>L13 residue of the NTS ligand</scene> | <scene name='72/721547/Ligand_protein_interactions/3'>L13 residue of the NTS ligand</scene> | ||