Sandbox Reserved 1177: Difference between revisions
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===Na+ Binding Pocket=== | ===Na+ Binding Pocket=== | ||
W321, which is positioned at the bottom of the hydrophobic pocket(green link from allie) sets the top of the Na+ ion binding pocket. The Na+ ion binding pocket acts as a negative allosteric site for G protein activity. When Na+ enters the Na+ ion binding pocket, it interacts with Asp 113, and shuts down the activity of the protein. When the G protein is in its active state, the Na+ ion binding pocket is collapsed, preventing the entrance of Na+. | W321, which is positioned at the bottom of the hydrophobic pocket(green link from allie), sets the top of the Na+ ion binding pocket. The Na+ ion binding pocket acts as a negative allosteric site for G protein activity. When Na+ enters the Na+ ion binding pocket, it interacts with Asp 113, and shuts down the activity of the protein. When the G protein is in its active state, the Na+ ion binding pocket is collapsed, preventing the entrance of Na+. | ||
<scene name='72/721548/Na_bind_pocket/12'>Na+ Binding Pocket</scene> | <scene name='72/721548/Na_bind_pocket/12'>Na+ Binding Pocket</scene> | ||
Revision as of 18:59, 25 March 2016
NTSR1-ELF, Rattus norvegicus
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