Integrin: Difference between revisions
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==Disease == | ==Disease == | ||
Defective integrin is the cause of the skin disease epidermolysis bullosa, of congenital muscular dystrophy. Overexpression of integrin is correlated with some types of cancer and enhanced bone resorption in osteoporosis<ref>PMID:8976799</ref>. Defective integrin is involved in periodontal diseases<ref>PMID:24662197</ref>. | Defective integrin is the cause of the skin disease epidermolysis bullosa, of congenital muscular dystrophy. Overexpression of integrin is correlated with some types of cancer and enhanced bone resorption in osteoporosis<ref>PMID:8976799</ref>. Defective integrin is involved in periodontal diseases<ref>PMID:24662197</ref>. | ||
== Structural highlights == | |||
The interactions of integrin with ligands are dependent on the presence of divalent ions<ref>PMID:10961914</ref>. | |||
</StructureSection> | </StructureSection> | ||
