Sandbox Reserved 1161: Difference between revisions

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The Human metabotropic glutamate receptor 5 transmembrane domain is a  
The Human metabotropic glutamate receptor 5 transmembrane domain is a  


== Structure==
== Structure ==
[[Image:STR.png|100 px|left|thumb|Figure Legend]]
[[Image:STR.png|100 px|left|thumb|Cross section view of mavoglurant in the binding pocket]]
=== Extracellular Domain ===
=== Extracellular Domain ===
=== Binding Pocket ===
[[Image: Organic with clipped surface.png|100 px|left|thumb|Figure Legend]]
<scene name='72/721532/Mavoglurant_in_pocket/4'>Mavoglurant Mavoglurant is in the 7 Transmembrane Domain Pocket. Also, the lysozyme is attached to the intercellular region of the 7 Transmembrane Domain.</scene>
=== Ionic Locks ===
This is the <scene name='72/726428/Ionic_lock/2'>Ionic Lock in inactive state</scene>.


This is the <scene name='72/721532/Ecl_trail_1/7'>Extracellular Loops ECL 1, 2, and 3 highlighted in purple</scene>
This is the <scene name='72/721532/Ecl_trail_1/7'>Extracellular Loops ECL 1, 2, and 3 highlighted in purple</scene>
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<scene name='72/721532/Ecl_trail_1/6'>Disulfide Bond The Disulfide bond is attached to Helix 3 and the Amino Acid chain connected to Helix 5 and the N terminus</scene>
<scene name='72/721532/Ecl_trail_1/6'>Disulfide Bond The Disulfide bond is attached to Helix 3 and the Amino Acid chain connected to Helix 5 and the N terminus</scene>
=== Binding Pocket ===
[[Image: Organic with clipped surface.png|100 px|left|thumb|Figure Legend]]
<scene name='72/721532/Mavoglurant_in_pocket/4'>Mavoglurant Mavoglurant is in the 7 Transmembrane Domain Pocket. Also, the lysozyme is attached to the intercellular region of the 7 Transmembrane Domain.</scene>


== Function and Pathway ==
== Function and Pathway ==


== Disease ==
== Disease ==
=== Fragile X ===
 
=== Parkinson's ===
=== Parkinson's ===
== Relevance ==
== Structural highlights ==
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
</StructureSection>
== References ==
<references/>