Sandbox Reserved 1161: Difference between revisions
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The Human metabotropic glutamate receptor 5 transmembrane domain is a | The Human metabotropic glutamate receptor 5 transmembrane domain is a | ||
== Structure== | == Structure == | ||
[[Image:STR.png|100 px|left|thumb| | [[Image:STR.png|100 px|left|thumb|Cross section view of mavoglurant in the binding pocket]] | ||
=== Extracellular Domain === | === Extracellular Domain === | ||
This is the <scene name='72/721532/Ecl_trail_1/7'>Extracellular Loops ECL 1, 2, and 3 highlighted in purple</scene> | This is the <scene name='72/721532/Ecl_trail_1/7'>Extracellular Loops ECL 1, 2, and 3 highlighted in purple</scene> | ||
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<scene name='72/721532/Ecl_trail_1/6'>Disulfide Bond The Disulfide bond is attached to Helix 3 and the Amino Acid chain connected to Helix 5 and the N terminus</scene> | <scene name='72/721532/Ecl_trail_1/6'>Disulfide Bond The Disulfide bond is attached to Helix 3 and the Amino Acid chain connected to Helix 5 and the N terminus</scene> | ||
=== Binding Pocket === | |||
[[Image: Organic with clipped surface.png|100 px|left|thumb|Figure Legend]] | |||
<scene name='72/721532/Mavoglurant_in_pocket/4'>Mavoglurant Mavoglurant is in the 7 Transmembrane Domain Pocket. Also, the lysozyme is attached to the intercellular region of the 7 Transmembrane Domain.</scene> | |||
== Function and Pathway == | == Function and Pathway == | ||
== Disease == | == Disease == | ||
=== Parkinson's === | === Parkinson's === | ||