Sandbox Reserved 1167: Difference between revisions
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An important interface stabilization interaction between helices I and VII occurs between [https://en.wikipedia.org/wiki/Serine Ser] 152 of Helix I and Ser 390 of Helix VII. Due to their close proximity to one another, they form an important <scene name='72/721537/Ser-ser_hydrogen_bond/2'>hydrogen bond</scene> which serves to stabilize the structure of GCGR. | An important interface stabilization interaction between helices I and VII occurs between [https://en.wikipedia.org/wiki/Serine Ser] 152 of Helix I and Ser 390 of Helix VII. Due to their close proximity to one another, they form an important <scene name='72/721537/Ser-ser_hydrogen_bond/2'>hydrogen bond</scene> which serves to stabilize the structure of GCGR. | ||
== Glucagon Binding == | == Glucagon Binding == | ||
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Because of GCGRs role in glucose homeostasis, it is a potential drug target for Type 2 diabetes. Specifically, molecules that antagoinze the glucagon receptor may be able to lower blood sugar levels. | Because of GCGRs role in glucose homeostasis, it is a potential drug target for Type 2 diabetes. Specifically, molecules that antagoinze the glucagon receptor may be able to lower blood sugar levels. | ||
</StructureSection> | |||
== References == | == References == | ||
<references/> | <references/> | ||
