Sandbox Reserved 1167: Difference between revisions

Revision as of 14:29, 30 March 2016 view source Olivia Murfield (talk \| contribs) 69 edits No edit summary ← Older edit		Revision as of 14:31, 30 March 2016 view source Olivia Murfield (talk \| contribs) 69 edits No edit summary Newer edit →
Line 9:		Line 9:
	== Function ==		== Function ==

	The Glucagon Receptor plays an important role in glucose homeostasis. During times of fasting (or low blood sugar) the pancreas dispatches glucagon to activate the GCGR in the liver. The [http://www.nature.com/nature/journal/v499/n7459/fig_tab/nature12393_F5.html binding of glucagon] stimulates [https://en.wikipedia.org/wiki/Gluconeogenesis gluconeogenesis], through adenylate cyclase that initiates protein kinase A (PKA) activity<ref>PMID:25674162</ref>. This pathway synthesizes glucose, elevating blood sugar levels.		The Glucagon Receptor plays an important role in glucose homeostasis. During times of fasting (or low blood sugar) the pancreas dispatches glucagon to activate the GCGR in the liver. The [http://www.nature.com/nature/journal/v499/n7459/fig_tab/nature12393_F5.html binding of glucagon] stimulates [https://en.wikipedia.org/wiki/Gluconeogenesis gluconeogenesis], through [https://en.wikipedia.org/wiki/Adenylyl_cyclase adenylate cyclase] that initiates [https://en.wikipedia.org/wiki/Protein_kinase_A protein kinase A] (PKA) activity<ref>PMID:25674162</ref>. This pathway synthesizes glucose, elevating blood sugar levels.

Navigation menu