Homocitrate synthase: Difference between revisions

From Proteopedia
Jump to navigationJump to search
No edit summary
No edit summary
Line 5: Line 5:


== Structural highlights ==
== Structural highlights ==
The HS active site is located in the interior of the N-terminal TIM-barrel domain. The metal ion is octahedrally coordinated to the protein and to the 2-oxoglutarate<ref>PMID:19776021</ref>.  
The HS active site is located in the interior of the N-terminal TIM-barrel domain. <scene name='46/465446/Cv/3'>Whole active site</scene>. The <scene name='46/465446/Cv/5'>metal ion is octahedrally coordinated to the protein and to the 2-oxoglutarate</scene><ref>PMID:19776021</ref>.  
</StructureSection>
</StructureSection>
== 3D Structures of homocitrate synthase ==
== 3D Structures of homocitrate synthase ==

Revision as of 11:29, 3 April 2016

Fission yeast homocitrate synthase Lys4 dimer complex with 2-oxoglutarate, Na+ (purple) and Zn+2 (grey) ions 3ivt

Drag the structure with the mouse to rotate

3D Structures of homocitrate synthase

Updated on 03-April-2016

3ivs – fyHS Lys4 – fission yeast
3ivt, 3ivu - fyHS Lys4 + 2-oxoglutarate
3mi3 - fyHS Lys4 + lysine
2ztj – TtHS + α-ketoglutarate – Thermus thermophilus
2zyf - TtHS + α-ketoglutarate + Mg
2ztk – TtHS + homocitrate
3a9i – TtHS + lysine

References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky