Sandbox Reserved 427: Difference between revisions
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<scene name='48/483884/Cartoondpb/1'>Vitamin D Binding Protein</scene>. is very similar to <scene name='48/483884/Cartoonhsa/1'>Human Serum Albumin(HSA)</scene>based on sequence similarity as well as a similar tertiary structure. The two proteins can both bind to actin, however HSA is unable to bind to Vitamin D3. Based on what you have learned about the binding nature DPB, and looking at the structures of the two proteins, hypothesize a reason HSA cannot bind to Vitamin D3. How can altering only a couple of amino acids so greatly alter the function and tertiary structure of proteins? | <scene name='48/483884/Cartoondpb/1'>Vitamin D Binding Protein</scene>. is very similar to <scene name='48/483884/Cartoonhsa/1'>Human Serum Albumin(HSA)</scene>based on sequence similarity as well as a similar tertiary structure. The two proteins can both bind to actin, however HSA is unable to bind to Vitamin D3. Based on what you have learned about the binding nature DPB, and looking at the structures of the two proteins, hypothesize a reason why HSA cannot bind to Vitamin D3. How can altering only a couple of amino acids so greatly alter the function and tertiary structure of proteins? | ||
==See Also== | ==See Also== | ||
*[[1kxp]] | *[[1kxp]] | ||
