Sandbox Reserved 427: Difference between revisions
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=====Alpha Helical Domains===== | =====Alpha Helical Domains===== | ||
The Vitamin D binding protein consists of <scene name='48/483884/Three_domains/2'>three alpha helical domains</scene> which are homologous to one another. <scene name='48/483884/Domain_i/2'>Domain I</scene> containing 10 alpha helices, <scene name='48/483884/Domain_ii/4'>Domain II</scene> 9, and <scene name='48/483884/Domain_iii/3'>Domain III</scene> 4 being shorter than the other domains. | The Vitamin D binding protein consists of <scene name='48/483884/Three_domains/2'>three alpha helical domains</scene> which are homologous to one another. <scene name='48/483884/Domain_i/2'>Domain I</scene> containing 10 alpha helices, <scene name='48/483884/Domain_ii/4'>Domain II</scene> 9, and <scene name='48/483884/Domain_iii/3'>Domain III</scene> 4 being shorter than the other domains. | ||
=====Vitamin D Binding Protein and Human Serum Albumin===== | |||
The overall structure is closely related to that of the human serum albumin, to which it is homologous. The proteins are very similar yet the three dimensional structure differs somewhat to facilitate binding. The differences are due to bends at the C-terminal alpha-helices of the first and second domains in addition to rotations at the loops connecting the first two domains. | |||
