Sandbox Reserved 427: Difference between revisions
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'''Biological Relevance of The Vitamin D Binding Site''' | '''Biological Relevance of The Vitamin D Binding Site''' | ||
Vitamin D hormone 1,25(OH)2D3 used to treat renal osteodystrophy, hypoparathyroidism and osteoporosis. | Vitamin D hormone 1,25(OH)2D3 used to treat renal osteodystrophy, hypoparathyroidism and osteoporosis. Administration of 1,25(OH)2D3 is limited due severe side effects, such as hypercalciuria, hypercalcemia and increased bone resorption. The analogs of 1,25(OH)2D3 are being created to increase the activity and bind affinity without out the negative side effects. | ||