Sandbox Reserved 1174: Difference between revisions

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=== Binding Pocket ===

The ligand shown in this structure is ONO-9780307~~. It~~ similar in structure to LPA, and was bound to LPA<sub>1</sub> for crystallization to visualize the binding pocket. <ref name= "Moolenaar" /> The <scene name='72/721545/Ligand/2'>binding pocket</scene> for LPA inside the receptor consists of both polar and nonpolar residues. There are <scene name='72/721545/All_polar_interactions/5'>polar</scene> residues on the N terminus and within the binding pocket (<scene name='72/721545/All_polar_interactions/6'>polar residues</scene>). There is also a <scene name='72/721545/Hydrophobic_pocket/3'>hydrophobic pocket</scene> that interacts with the long acyl chain of LPA.

The ligand shown in this structure, ONO-9780307, has a similar structure to LPA, and was bound to LPA<sub>1</sub> for crystallization to visualize the binding pocket. <ref name= "Moolenaar" /> The <scene name='72/721545/Ligand/2'>binding pocket</scene> for LPA inside the receptor consists of both polar and nonpolar residues. There are <scene name='72/721545/All_polar_interactions/5'>polar</scene> residues on the N terminus and within the binding pocket (<scene name='72/721545/All_polar_interactions/6'>polar residues</scene>). There is also a <scene name='72/721545/Hydrophobic_pocket/3'>hydrophobic pocket</scene> that interacts with the long acyl chain of LPA.

=== Sphingosine-1-Phosphate Receptor ===

Sandbox Reserved 1174: Difference between revisions

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@@ Line 28: / Line 28: @@
 === Binding Pocket ===
-The ligand shown in this structure is ONO-9780307. It similar in structure to LPA, and was bound to LPA<sub>1</sub> for crystallization to visualize the binding pocket. <ref name= "Moolenaar" /> The <scene name='72/721545/Ligand/2'>binding pocket</scene> for LPA inside the receptor consists of both polar and nonpolar residues. There are <scene name='72/721545/All_polar_interactions/5'>polar</scene> residues on the N terminus and within the binding pocket (<scene name='72/721545/All_polar_interactions/6'>polar residues</scene>). There is also a <scene name='72/721545/Hydrophobic_pocket/3'>hydrophobic pocket</scene>  that interacts with the long acyl chain of LPA.
+The ligand shown in this structure, ONO-9780307, has a similar structure to LPA, and was bound to LPA<sub>1</sub> for crystallization to visualize the binding pocket. <ref name= "Moolenaar" /> The <scene name='72/721545/Ligand/2'>binding pocket</scene> for LPA inside the receptor consists of both polar and nonpolar residues. There are <scene name='72/721545/All_polar_interactions/5'>polar</scene> residues on the N terminus and within the binding pocket (<scene name='72/721545/All_polar_interactions/6'>polar residues</scene>). There is also a <scene name='72/721545/Hydrophobic_pocket/3'>hydrophobic pocket</scene>  that interacts with the long acyl chain of LPA.
 === Sphingosine-1-Phosphate Receptor ===