Sandbox Reserved 1174: Difference between revisions
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=== Binding Pocket === | === Binding Pocket === | ||
The ligand shown in this structure, ONO-9780307, has a similar structure to LPA, and was bound to LPA<sub>1</sub> for crystallization to visualize the binding pocket. <ref name= "Moolenaar" /> The <scene name='72/721545/Ligand/2'>binding pocket</scene> for LPA | The ligand shown in this structure, ONO-9780307, has a similar structure to LPA, and was bound to LPA<sub>1</sub> for crystallization to visualize the binding pocket. <ref name= "Moolenaar" /> The <scene name='72/721545/Ligand/2'>binding pocket</scene> for LPA consists of both polar and nonpolar residues. <scene name='72/721545/All_polar_interactions/5'>Polar</scene> residues are located on the N terminus and within the binding pocket (<scene name='72/721545/All_polar_interactions/6'>polar residues</scene>). There is also a <scene name='72/721545/Hydrophobic_pocket/3'>hydrophobic pocket</scene> that interacts with the long acyl chain of LPA. | ||
=== Sphingosine-1-Phosphate Receptor === | === Sphingosine-1-Phosphate Receptor === | ||
