Sandbox Reserved 1174: Difference between revisions
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== Endocannabinoids == | == Endocannabinoids == | ||
The endocannabinoid system regulates a variety of physiological processes including appetite, pain sensation, mood, and memory. Endocannabinoids, the natural ligands for cannabinoid receptors, are similar in structure to lysophosphatidic acid.<ref name= "Chrencik"/> Both the cannabinoid receptors and the LPA receptors have a preference for long unsaturated acyl chains.<ref name= "Chrencik"/> The polar amino acid <scene name='72/721545/210/1'>Trp210</scene> in the binding pocket of LPA<sub>1</sub> is unique to the lysophospholipid and cannabinoid receptors. | The endocannabinoid system regulates a variety of physiological processes including appetite, pain sensation, mood, and memory. Endocannabinoids, the natural ligands for cannabinoid receptors, are similar in structure to lysophosphatidic acid.<ref name= "Chrencik"/> Both the cannabinoid receptors and the LPA receptors have a preference for long unsaturated acyl chains.<ref name= "Chrencik"/> The polar amino acid <scene name='72/721545/210/1'>Trp210</scene> in the binding pocket of LPA<sub>1</sub> is unique to the lysophospholipid and cannabinoid receptors, suggesting that they are related. | ||
[[Image:2-AG.png|220px|right|thumb|'''Figure 4:''' 2-arachidonylglycerol (2-AG)]] | [[Image:2-AG.png|220px|right|thumb|'''Figure 4:''' 2-arachidonylglycerol (2-AG)]] | ||