Met repressor: Difference between revisions
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{{STRUCTURE_1mjo| PDB=1mjo | SIZE=400| SCENE= |right|CAPTION=EcMR (mutant) complex with corepressor SAM Ca+2 ion (green) and DNA [[1mjo]] }} | {{STRUCTURE_1mjo| PDB=1mjo | SIZE=400| SCENE= |right|CAPTION=EcMR (mutant) complex with corepressor SAM Ca+2 ion (green) and DNA [[1mjo]] }} | ||
== Function == | |||
'''Met repressor''' (MR) interacts with the DNA operator (Met box) repressing methionine synthesis. The coreppressor of MR is S-adenosyl methionine (SAM) which is a product of methionine synthesis. Binding of SAM to MR increases the repressor affinity to the DNA thus halting methionine synthesis<ref>PMID:11696548</ref>. For additional details see<br /> | |||
'''Met repressor''' (MR) interacts with the DNA operator (Met box) repressing methionine synthesis. The | |||
[[Taylor met repressor]]<br /> | [[Taylor met repressor]]<br /> | ||
[[Joe Granger Methionine Repressor: Escherichia coli]]. | [[Joe Granger Methionine Repressor: Escherichia coli]]. | ||
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[[1mjl]], [[1mjp]] – EcMR (mutant) + SAM<br /> | [[1mjl]], [[1mjp]] – EcMR (mutant) + SAM<br /> | ||
[[1mj2]], [[1mjo]], [[1mjq]] – EcMR (mutant) + SAM + DNA<br /> | [[1mj2]], [[1mjo]], [[1mjq]] – EcMR (mutant) + SAM + DNA<br /> | ||
== References == | |||
<references/> | |||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||