Met repressor: Difference between revisions
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{{STRUCTURE_1mjo| PDB=1mjo | SIZE=400| SCENE= |right|CAPTION=EcMR (mutant) complex with corepressor SAM Ca+2 ion (green) and DNA [[1mjo]] }} | {{STRUCTURE_1mjo| PDB=1mjo | SIZE=400| SCENE= |right|CAPTION=EcMR (mutant) complex with corepressor SAM Ca+2 ion (green) and DNA [[1mjo]] }} | ||
== Function == | == Function == | ||
'''Met repressor''' (MR) interacts with the DNA operator (Met box) repressing methionine synthesis. The | '''Met repressor''' (MR) interacts with the DNA operator (Met box) repressing methionine synthesis. The co-repressor of MR is S-adenosyl methionine (SAM) which is a product of methionine synthesis. Binding of SAM to MR increases the repressor affinity to the DNA thus halting methionine synthesis<ref>PMID:8092669</ref>. For additional details see<br /> | ||
[[Taylor met repressor]]<br /> | [[Taylor met repressor]]<br /> | ||
[[Joe Granger Methionine Repressor: Escherichia coli]]. | [[Joe Granger Methionine Repressor: Escherichia coli]]. | ||
