Sandbox Reserved 1176: Difference between revisions
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===Ligand Binding Pocket=== | ===Ligand Binding Pocket=== | ||
On the extracellular side of the protein is the | On the extracellular side of the protein is the | ||
<scene name='72/721547/Hydrophobic_binding_pocket/5'>hydrophobic binding pocket</scene>. | <scene name='72/721547/Hydrophobic_binding_pocket/5'>hydrophobic binding pocket</scene>. <ref name="SONT"/> | ||
One key residue in this pocket is a Phenylalanine at position 358, which takes part in a network of hydrophobic stacking interactions. These interactions stabilize the Trp321 and Tyr324 residues allowing Tyr324 to interact with the '''[https://en.wikipedia.org/wiki/C-terminus C-terminal]''' | One key residue in this pocket is a Phenylalanine at position 358, which takes part in a network of hydrophobic stacking interactions. These interactions stabilize the Trp321 and Tyr324 residues allowing Tyr324 to interact with the '''[https://en.wikipedia.org/wiki/C-terminus C-terminal]''' | ||
<scene name='72/721547/Ligand_protein_interactions/7'>Leu13 residue of the NTS ligand</scene> | <scene name='72/721547/Ligand_protein_interactions/7'>Leu13 residue of the NTS ligand</scene> | ||
