Sandbox Reserved 1176: Difference between revisions
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===Active-Like State=== | ===Active-Like State=== | ||
The, six amino acids mutations for thermostabilization <ref name="SONT"/> were A86L, E166A, G215A, L310A, F358A, and V360A. This protein was found to have NTS affinity similar to that of wild tpye NTSR1, and was named <scene name='72/721547/Ntsr1-gw5/8'>NTSR1-GW5</scene>. Along with this, the Na+ ion binding pocket was | The, six amino acids mutations for thermostabilization <ref name="SONT"/> were A86L, E166A, G215A, L310A, F358A, and V360A. This protein was found to have NTS affinity similar to that of wild tpye NTSR1, and was named <scene name='72/721547/Ntsr1-gw5/8'>NTSR1-GW5</scene>. Along with this, the Na+ ion binding pocket was collapsed in this protein. However, NTSR1-GW5 did not have G-protein activity <ref name="SONT"/>. | ||
===Active State=== | ===Active State=== | ||
