Sandbox Reserved 1176: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
No edit summary
No edit summary
Line 24: Line 24:
===Active-Like State===
===Active-Like State===


The, six  amino acids mutations for thermostabilization <ref name="SONT"/> were A86L, E166A, G215A, L310A, F358A, and V360A. This protein was found to have NTS affinity similar to that of wild tpye NTSR1, and was named <scene name='72/721547/Ntsr1-gw5/8'>NTSR1-GW5</scene>. Along with this, the Na+ ion binding pocket was collapsed in this protein. However, NTSR1-GW5 did not have G-protein activity <ref name="SONT"/>.  
The six  amino acids mutations for thermostabilization <ref name="SONT"/> were A86L, E166A, G215A, L310A, F358A, and V360A. This protein was found to have NTS affinity similar to that of wild tpye NTSR1, and was named <scene name='72/721547/Ntsr1-gw5/8'>NTSR1-GW5</scene>. Along with this, the Na+ ion binding pocket was collapsed in this protein. However, NTSR1-GW5 did not have G-protein activity <ref name="SONT"/>.  


===Active State===
===Active State===
Retrieved from "https://proteopedia.org/Sandbox_Reserved_1176"