Sandbox WWC8: Difference between revisions
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[[Image:Structural Features of NP.jpg]] | [[Image:Structural Features of NP.jpg]] | ||
==Characterization of NP Binding Interactions== | ==Characterization of NP Binding Interactions and Functions in Viral Replication Cycle== | ||
====RNA binding activity==== | ====RNA binding activity==== | ||
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====Other Binding Interactions==== | ====Other Binding Interactions==== | ||
''NP-Importin α'' | |||
''NP-CRM1'' | |||
''NP-F-actin'' | |||
''NP-M1'' | |||
''NP Phosphorylation Profile'' | |||
<references/> | |||
==Identification of Antiviral Drug Targets on NP== | ==Identification of Antiviral Drug Targets on NP== | ||
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10] S. Boivin, S. Cusack, R.W.H. Ruigrok, D.J. Hart, Influenza A Virus Polymerase: Structural Insights into Replication and Host Adaptation Mechanisms, J. Biol. Chem. 285 (2010) 28411–28417. doi:10.1074/jbc.R110.117531. | 10] S. Boivin, S. Cusack, R.W.H. Ruigrok, D.J. Hart, Influenza A Virus Polymerase: Structural Insights into Replication and Host Adaptation Mechanisms, J. Biol. Chem. 285 (2010) 28411–28417. doi:10.1074/jbc.R110.117531. | ||
[11] P. Digard, D. Elton, K. Bishop, E. Medcalf, A. Weeds, B. Pope, Modulation of Nuclear Localization of the Influenza Virus Nucleoprotein through Interaction with Actin Filaments, J Virol. 73 (1999) 2222–2231. | |||
[12] G. Neumann, M.R. Castrucci, Y. Kawaoka, Nuclear import and export of influenza virus nucleoprotein., J. Virol. 71 (1997) 9690–9700. | |||
