MECDP synthase: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Michal Harel (talk | contribs) No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
<StructureSection load='1gx1' size='400' side='right' scene='' caption='Se-Met MECDP synthase trimer complex with CDP (stick model), sulfate, Mn+2 (purple) and Zn+2 (grey) ion, [[1gx1]]'> | |||
== Function == | == Function == | ||
'''MECDP synthase''' (MECPS) participates in mevalonate-independent steroid biosynthesis. It converts 2-phospho-4-(cytidine 5’-diphospho)-2-C-methyl-D-erythritol (2P-CDME) to 2-C-methyl-D-erythritol 2, 4-cyclodiphosphate (MECP) and CMP. MECPS contains metal binding sites which are required for catalysis<ref>PMID:11786530</ref>. | '''MECDP synthase''' (MECPS) participates in mevalonate-independent steroid biosynthesis. It converts 2-phospho-4-(cytidine 5’-diphospho)-2-C-methyl-D-erythritol (2P-CDME) to 2-C-methyl-D-erythritol 2, 4-cyclodiphosphate (MECP) and CMP. MECPS contains metal binding sites which are required for catalysis<ref>PMID:11786530</ref>. | ||
| Line 8: | Line 9: | ||
== Structural highlights == | == Structural highlights == | ||
MECPS active site is located in a cleft between 2 subunits and contains the metal ions<ref>PMID:11997478</ref>. | MECPS active site is located in a cleft between 2 subunits and contains the metal ions<ref>PMID:11997478</ref>. | ||
</StructureSection> | |||
==3D structures of MECDP synthase== | ==3D structures of MECDP synthase== | ||
Revision as of 08:25, 25 April 2016
| ||||||||||||
3D structures of MECDP synthase
Updated on 25-April-2016
