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'''Unreleased structure'''


The entry 5ign is ON HOLD
==Crystal structure of human BRD9 bromodomain in complex with LP99 chemical probe==
 
<StructureSection load='5ign' size='340' side='right' caption='[[5ign]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
Authors: Tallant, C., Clark, P.G.K., Vieira, L.C.C., Newman, J.A., Krojer, T., Nunez-Alonso, G., Picaud, S., Fedorov, O., Dixon, D.J., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Brennan, P.E., Knapp, S., Structural Genomics Consortium (SGC)
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5ign]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IGN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IGN FirstGlance]. <br>
Description: Crystal structure of human BRD9 bromodomain in complex with LP99 chemical probe
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6B2:N-[(2R,3S)-2-(4-CHLOROPHENYL)-1-(1,4-DIMETHYL-2-OXO-1,2-DIHYDROQUINOLIN-7-YL)-6-OXOPIPERIDIN-3-YL]-2-METHYLPROPANE-1-SULFONAMIDE'>6B2</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ign FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ign OCA], [http://pdbe.org/5ign PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ign RCSB], [http://www.ebi.ac.uk/pdbsum/5ign PDBsum]</span></td></tr>
[[Category: Nunez-Alonso, G]]
</table>
== Function ==
[[http://www.uniprot.org/uniprot/BRD9_HUMAN BRD9_HUMAN]] May play a role in chromatin remodeling and regulation of transcription.  
__TOC__
</StructureSection>
[[Category: Arrowsmith, C H]]
[[Category: Bountra, C]]
[[Category: Brennan, P E]]
[[Category: Clark, P G.K]]
[[Category: Delft, F von]]
[[Category: Dixon, D J]]
[[Category: Edwards, A M]]
[[Category: Fedorov, O]]
[[Category: Fedorov, O]]
[[Category: Vieira, L.C.C]]
[[Category: Picaud, S]]
[[Category: Knapp, S]]
[[Category: Knapp, S]]
[[Category: Clark, P.G.K]]
[[Category: Krojer, T]]
[[Category: Krojer, T]]
[[Category: Bountra, C]]
[[Category: Newman, J A]]
[[Category: Arrowsmith, C.H]]
[[Category: Nunez-Alonso, G]]
[[Category: Von Delft, F]]
[[Category: Picaud, S]]
[[Category: Edwards, A.M]]
[[Category: Structural genomic]]
[[Category: Dixon, D.J]]
[[Category: Brennan, P.E]]
[[Category: Newman, J.A]]
[[Category: Structural Genomics Consortium (Sgc)]]
[[Category: Tallant, C]]
[[Category: Tallant, C]]
[[Category: Vieira, L C.C]]
[[Category: Chromatin regulator]]
[[Category: Lysine-acetylated histone binding]]
[[Category: Sgc]]
[[Category: Transcription]]

Revision as of 20:37, 11 May 2016

Crystal structure of human BRD9 bromodomain in complex with LP99 chemical probe

5ign, resolution 1.70Å

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